CV

Education

Work experience

08.2022-now Senior Computational Biologist in Biological Systems Group in the Okinawa Institute of Science and Technology.
Analysis of multi-omics data from various environmental and host-related microbial communities. Development of new approaches for the mechanistic understanding of the principles guiding microbial community evolution.

11.2015-now Senior Researcher in the Laboratory of Molecular and Ion Physics in the Moscow Institute of Physics and Technology.
Development of computational infrastructure for collection, storage, retrieval and analysis of the brain tumor tissue fragments molecular profiles obtained with various ambient mass-spectrometry methods. Development new machine learning and AI approaches for the tumor boundary detection and estimation of the sample tumor cell percentage from the ambient mass-spectrometry spectra.

07.2019-07.2022 Researcher, School of Biochemistry, University of Liverpool.

07.2014-11.2019 Head of the laboratory of Mechanisms of genome functioning in the Institute of the cell biophysics RAS.

08.2013-06.2014 Lead researcher in the laboratory of Mechanisms of genome functioning in the Institute of the cell biophysics RAS.

04.2011-08.2013 Senior researcher in the laboratory of Mechanisms of genome functioning in the Institute of the cell biophysics RAS.

07.2009-03.2011  Senior software developer in BioMedCAD project, School of Informatics, The University of Edinburgh. Development of PRTR annotation workflow and text-mining backend.

05.2008-06.2009 Leading Informatics Researcher in ROBuST SABR project, School of Informatics, The University of Edinburgh.
Development of experimental data archive and datamart. Development of modeling pipeline.

09.2005-04.2008 Research fellow in Scottish Centre for Systems Biology and Edinburgh Centre for Bioinformatics School of Informatics The University of Edinburg.
Development of Edinburgh Pathway editor and related plug-ins, development of Edinburgh Chemical Ontology, development of biological network static properties analysis algorithm, analysis of human metabolic network, analysis of interferon signaling pathway. Coordination of SBGN activities in ECB with EPE development, development of Edinburgh Pathway notation. Development of parameter space exploration and fitting facility for SBSI. Students supervision.

08.2005-03.2011 Researcher in the laboratory of Mechanisms of genome functioning Institute of the cell biophysics RAS
Analysis of promoter-protein recognition on the basis of E.coli sigma-70 promoter database. Development of algorithm for fast electrostatic properties of long DNA fragments evaluation. Analysis of electrostatic profiles of promoter regions of chromosome of E. coli.

04.2002-08.2003 EMP Project Lead Software Developer
Development of web service and database for biochemical information for human metabolism reconstruction project.

09.1999-09.2000 EMP Project Software developer
Development module for statistical analysis of EMP database.

05.1998-08.2005 Junior researcher in the laboratory of Mechanisms of genome functioning Institute of the cell biophysics RAS
Analysis of promoter-protein recognition on the basis of E.coli sigma-70 promoter database. Development of algorithm for the fast evaluation of electrostatic properties of long DNA fragments. Analysis of electrostatic profiles of promoter regions of chromosome of E. coli.

02.1997-02.1998 Visiting student in the Plant Genetics Department, Weizmann Institute of Science
Analysis of ligand-protein contacts in the 3-D complexes (LPC software in any PDB mirror), analysis of influence of type of substitution on the structure of mutant protein modeling of the 3-D structure of the protein on the basis of sequence homology.

09.1995- 02.1997 Post-graduate student in the laboratory of The cell and tissue grow of the Institute of theoretical and experimental biophysics RAS.
Research: investigation of the rhythm of spontaneously beating cardiomyocytes in vitro.
Methods:  on-line and off-line signal analysis, signal analysis on the basis of nonlinear dynamical and statistical methods.

Skills

Publications

Talks

Teaching